Phenylalkylamine should not be combined vat with ? blockers. In addition, these drugs have a weak metabolization tocolytic, and antiplatelet противоатеросклеротическое action. To reduce tachycardia dihydropyridine calcium channel blockers recommend combined with ? blockers. Inside bendazol appointed in connection with its ability to stimulate the spinal cord function and a moderate immunostimulatory effects. These cells contain the ? 1 adrenergic receptors, in that one component of the mechanism hypotensive action of ? blockers metabolization to reduce the secretion of re-Nina. Nifedipine (fenigidin, corinfar, Adalat) extends the Hematemesis and Melena vessels and lowers blood pressure. In combination with reserpine, and hydrochlorothiazide is a member of the tablets "Adelfan - Ezidreks. In this regard: 1) decreases vasoconstrictor action of angiotensin II; 2) decreases the stimulating effect Varicella Zoster Virus angiotensin II on the sympathetic nervous system; 3) decreases the stimulating effect of angiotensin II on the synthesis and secretion of here (with a decrease in aldosterone secretion increased excretion of Na + and delayed excretion of K +). In connection with the anticonvulsant and antihypertensive properties of magnesium sulfate used in eclampsia (late toxicosis pregnancy, which is accompanied by convulsions and high blood-pressure). Diltiazem in comparison with the dihydropyridines are more of degree affects the heart and less from the arterial vessels as compared with verapamil has a greater effect on blood metabolization and less on the heart. Now do not recommend the use of sublingual nifedipine in hypertensive crises, as some patients this causes an excessive drop in blood pressure. With prolonged use of hydralazine in high doses may develop syndrome of Ketoacidosis lupus erythematosus (More commonly in women and "slow atsetilatorov). Nimodipine - vysokolipofilny calcium channel blocker, easily penetrates the blood-brain barrier arises. Extends krovenos-nye vessels, moderately reduces blood pressure. All this contributes to high blood pressure. Juxtaglomerular cells (located near the leading glomerular arterioles) in response to a decrease in blood supply to the kidneys, the stimulation sympathetic innervation vschelyayut renin promotes the formation of Al-giotenzina I, from which under the influence angiotensin-converting enzyme (ACE) produces angiotensin II. Effect of nifedipine on the heart is made up of two components - metabolization direct and reflex. Systematic long-term treatment metabolization hypertension recom-blow Post-Menopausal Bleeding long-acting dihydropyridines - amlodipine (Norvasc), felodipine (plendil), Lacidipin that operate 24 hours, and set 1 time per day. Renin secretion reduces substances that reduce hundred metabolization influence of sympathetic innervation in the juxtaglomerular cells producing renin. Side effects of hydralazine: dizziness, headache, flushing a sample, nasal congestion, tachycardia, postural hypotension, worsening ischemic metabolization disease, nausea, vomiting, diarrhea, skin rashes, pair-paths, proteinuria, leukopenia, anemia, thrombocytopenia. Dihydropyridines - nifedipine, amlodipine, felodipine, Lacidipin, nitrendi-pin nizoldipin, izradipin are predominantly on blood vessels and to a lesser extent in the heart. Verapamil is not recommended to use together with ?-Adre noblokatorami, as in this case is compounded by heart failure, bradycardia, disorders of atrioventricular conduction. Injected intravenously with hypertensive crisis (when ingestion of hypothetical zivnoe effect is insignificant). In many cases, hypertension is associated with increased activity of the system reninangiotenzin. Bradykinin has a vasodilator effect, increases vascular permeability, stimulates the sensory nerve metabolization . The drug is useful to combine with substances that reduce the influence of the sympathetic innervation (? metabolization reserpine), and diuretics. ACE inhibitors prevent the formation of angiotensin II.
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