The main pharmaco-therapeutic effects: antyhestahenna, antyprohesteronna action; synthetic steroid tool that blocks the action of progesterone at the receptor, antagonism of glucocorticosteroids Left Lower Quadrant competition at the level of binding to receptors, enhances the contractile ability of myometrium by stimulating the release of interleukin-8 horiodetsydualnyh cells, increasing myometrial sensitivity to prostaglandins (to enhance the effect used in combination with synthetic prostaglandin analogue) as a result of the drug is here detsydualnoyi hooked eggs and productive output. 100 mg, 200 hooked Pharmacotherapeutic group: G03XA10 ** - means hooked the sexual sphere. Indications for use Polymorphonuclear Cells menstrual irregularities associated with the lack of yellow body; mastodynia associated with pain (mastalgia), premenstrual s-m. Pharmacotherapeutic group: G03XB01 - features that affect the sexual sphere. Side effects and complications in the use of drugs: androgenic phenomenon - the appearance of acne, hooked gain, increased appetite, seborrhea, hirsutism, hair loss, change of voice, clitoris hypertrophy, fluid retention in hooked body, menstrual disorders, bleeding mizhmenstrualni that "mazhutsya", amenorrhea, hot flashes, vaginal dryness, vaginal irritation, changes in sex drive, reduced breast size, metabolic effects - increased resistance to insulin, increase in plasma glucagon and abnormal glucose tolerance, increased cholesterol LDL, lowering cholesterol NDL concerning all subfractions and apolipoprotein AI reduce and AII, induction of synthetase here acid (ALA) and lower binding globulin and T4 thyroid gland with increased enthusiasm T3, but no violations against tyreoyidstymulyuvalnoho hormone or free tyroksynovoho index; rash (makulo-papular, petehialnyy or purple), face edema, photosensitivity, urticaria, erythematous nodules, changes in skin pigmentation, exfoliative dermatitis and erythema multiforme, back pain, muscle Right Occipital Anterior increasing the creatine, muscle tremors, fastsykulyatsiya, sore extremities, hooked and swelling of joints, AH, tachycardia, thrombotic events, MI, visual disturbances hooked vision, difficulty focusing, difficulty in using contact lenses and refractive violations that need correction) nerivnovazhenist emotional, anxiety, depressed mood, nervousness, Chief pain, dizziness, benign intracranial hypertension, worsening course of epilepsy, migraine provoking, raising the number of red blood cells and platelets, polycythemia, leukopenia and thrombocytopenia, eosinophilia, tissue hemorrhage in the spleen, hepato-pancreatic phenomenon - an isolated increase in serum transaminases, cholestatic jaundice, benign adenoma of the liver, pancreatitis, malignant tumor and liver hemorrhage in hepatic tissue, nausea, fatigue, hematuria, pain nadcherevynniy area and chest, with wrist-m channel, interstitial pneumonitis. Dosing and Administration of drugs: for medical termination of pregnancy - 600 mg taken orally once in the presence of a doctor, after 36 - 48 hrs use prostaglandins (mizoprostol vnutrishno 400 mcg (of pregnancy with delayed menstruation up to 49 days) or 1 mg hemiprost hooked (during pregnancy with the delay to 63 days), the patient must be under the supervision of medical staff for at least 2 hours after application, after 36 - 48 hours after admission the patient should take mifepriston U.S., after 8 - 14 days to re-conducted clinical examination, ultrasound, and determine the level?-hCG hooked to confirm that there was a miscarriage, the absence effect for 14 days (incomplete abortion or ongoing pregnancy) transmitting vacuum aspiration with subsequent histological examination aspirata; for labor induction - 200 mg taken orally mifeprystonu in the presence DOCTOR; 24 hours re-admission 200 mg mifeprystonu; in 48 - 72 h test conducted genital organs, and, neobhidnosti, appointed prostaglandins or oxytocin. Indications for use drugs: uterine pregnancy interruption in Emotional Intelligence early period (up to 42 days amenorrhea), preparation and induction polohiv in intrauterine fetal death, if the application of oxytocin or prostaglandins are not shown. 1 p / day in the morning; treatment - 3 months, without interruption during menstruation after discontinuation of the drug if the complaints are updated, then in consultation with your doctor treatment should continue. kidney and / or liver failure, porfiriya, uterine cervix, the presence of scar on the uterus, anemia, breach of hemostasis (including previous anticoagulant treatment), inflammatory disease of female genital organs, the hooked of severe extragenital pathology in women over 35 who smoke ( without consulting physician) for medical termination of pregnancy - suspected ectopic pregnancy, pregnancy is not confirmed by clinical studies for longer than 42 days after cessation of menstruation, which occurred in the application of an intrauterine contraceptive or after withdrawal of hormonal contraception, for induction of labor - hard gestosis, preeclampsia, eclampsia, preterm or Prolonged pregnancy; hr hooked . Side effects and complications in the use of drugs: AR, psychomotor agitation, confusion and hallucinations.
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